Initial studies in rats caused concerns over GLP-1 RAs causing thyroid cancer, but human studies are less clear on whether it is a concern.[ref] Decreased risk of substance abuse: A large 2026 study using data from the VA showed that GLP-1 RA drugs reduce the risk of developing a substance addiction (drugs, alcohol)
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Additionally, both semaglutide and tirzepatide showed promise in improving metabolic dysfunction-associated steatotic liver disease (MASLD), mitigating systemic inflammation, and contributing to improvements in liver-related outcomes, including steatosis resolution and fibrosis-related endpoints, in clinical trials
Better blood sugar control, which may support individuals with prediabetes or Type 2 diabetes
Based at the University of Lausanne in Switzerland, Thorens had a long-standing interest in insulin resistance and diabetes from both an academic and clinical perspective
If screening is positive, referral to cessation programs or counseling services can provide additional support
