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Trends in the prevalence and incidence of clinical Alzheimer's dementia over time Several studies indicate that the prevalence (i.e., proportion) 296 , 399 , 400 , 401 , 426 , 427 , 428 , 429 and incidence 337 , 427 , 428 , 429 , 430 , 431 , 432 , 433 , 434 , 435 , 436 of Alzheimer's and other dementias in the U.S

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The difference is what reaches the dermis