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The main mechanism of action of Phentermine/Topiramate extended release(ER) is possibly the alteration of various neurotransmitters, including inhibition of voltage-dependent sodium channels, glutamate receptors, and carbonic anhydrase as well as potentiation of -aminobutyrate activity (83).Two large randomized, double-blind, placebo-controlled trials took place (EQUIP and CONQUER) followed by a 2-year extension trial (SEQUEL)

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This product is intended for use by qualified healthcare professionals or under the guidance of a licensed medical provider

For instance, the inclusion of vegetable extracts such as curcumin has shown the potential to increase the amount of serum glutathione in human osteoarthritic knees

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Plasma EV proteomic analysis Human plasma sample Plasma samples were obtained from the study participants at KNUH