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For a cardiovascular performance assay, six endpoints were chosen to evaluate the cardiovascular performance in the zebrafish larvae: the heart rate and time interval in ventricles, stroke volume, cardiac output, ejection fraction, and shortening fraction

Chronic treatment of exendin-4 affects cell proliferation and neuroblast differentiation in the adult mouse hippocampal dentate gyrus

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Washington (DC: National Academy of Sciences (2015)

For a patient, that combination reads as a genuine trade-off rather than a clean win