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SLC25A40 knockdown destabilized ETC Complexes I, II, and III, elevated cytosolic and mitochondrial ROS, and upregulated Gclc and Gclm genes essential for GSH synthesis

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When GSTM3 was upregulated, the activity of ROS was obviously reduced than that in the normal group (Figures 6C,D)

Ping Li, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers