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Kuffner, McNeil's vice president for medical affairs, said in an interview that the company changed its dosing instructions after hearing the discussion at the 2009 advisory committee

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The 95% CIs were calculated manually when not reported in the original publications ( I 2 was calculated to quantify heterogeneity and inconsistency between studies

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(7) That type of motility is a basic requirement for sprouting angiogenesis, where endothelial cells need to move into hypoxic tissue and organize into new tubes