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doi:10.1038/ncomms9918 63

Efficacy and safety of tirzepatide, dual GLP-1/GIP receptor agonists, in the management of type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials

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Clinical Evidence and Safety Concerns in Teenage Patients Published trials on GLP-1 agents in adolescents remain sparse compared to adult data

GLP-1 crosses the blood-brain barrier in limited amounts, but the brain also produces its own GLP-1 through neurons in the nucleus tractus solitarius (NTS) of the brainstem