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Further evidence comes from a randomized, double-blind, placebo-controlled Phase Ib clinical trial that also evaluated the efficacy and safety of setmelanotide in obese patients harboring heterozygous LOF variants in MC4R (either complete or partial LOF

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Reduces the Symptoms of Chronic Fatigue and Fibromyalgia Chronic fatigue and fibromyalgia are complex conditions that often dont respond well to standard treatments

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