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similarly, diminished protein levels of SOD2 were reported in HepG2 cells treated with oleic acid (Sharma et al

Preclinical studies have demonstrated improved physical performance, restored renal function, and enhanced coat density in aged animal subjects following peptide administration all hallmarks of biological rejuvenation

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These effects include promoting cell survival/proliferation, 52,53 migration/invasion, 53,54 oncogenic transformation, 55,56 and epithelial-to-mesenchymal transition, 54,57,58 as well as promoting tumor angiogenesis 59 and lymphangiogenesis 60 and enhancing a cancer stem cell-like phenotype