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Pending the results of larger-scale clinical trials of GLP-1RAs already used in the clinic, the ongoing development of next-generation incretin mimetics opens up opportunities to improve their access to the brain and enhance neuroprotection [87]

Although GLP-1RAs can play a favorable role in improving heart failure based on pre-clinical studies, whereas some clinical evidence relevantly have reported that GLP-1RAs treatment could be associated with adverse heart failure events, eg

Studies document its interaction with stress response and sleep architecture

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The appeal is obvious: they're cheaper, no prescription is needed, and they're framed as doing the same job as expensive, prescription-only injections

Ozempic is part of a drug class known as GLP-1 medications, which mimic gut hormones that help regulate blood sugar and suppress appetite