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They are also prescribed for patients who are overweight, i.e ., those with a BMI of greater than 27, and who also have one weight-related condition, such as hypertension, hyperlipidemia or sleep apnea

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Kapitza C, Forst T, Coester HV, et al

The honest answer is that no head-to-head RCT comparing MT2 and MT1 for cosmetic tanning in the same population exists

No single receptor accounts for its activity