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If retatrutide is approved in the future, switching guidance would need to come from official prescribing information and clinical assessment

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Medications such as metformin [Glucophage], phentermine [Adipex-P], topiramate [Topamax], bupropion [Wellbutrin], and naltrexone [Revia] (sometimes used alone or in combination, [such as Contrave]) can be effective and are often available as inexpensive generics, sometimes for as little as $10 to $20 per month

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