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We compared logistic regression with three different machine learning models using distinct algorithms: LightGBM, SVC, and ANNs

CCI, Charlson Comorbidity Index

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Work with the FDA and other agencies to update guidelines for lifestyle interventions in pediatric clinical trials that incorporate state-of-the-art approaches to quantifying, monitoring, and evaluating physical activity, adherence to diet, and accurate measurement of body composition beyond the current reliance on the body mass index (BMI), a suboptimal metric of overweight and obesity in adolescents

This allows for the isolated study of GLP-2T's interaction with each receptor target without interference from other signaling systems