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Hetrick SE, McKenzie JE, Bailey AP, Sharma V, Moller CI, Badcock PB, et al

Why gastrointestinal events are often discussed Gastrointestinal side effects receive a lot of attention in Retatrutide research because incretin-related compounds interact with pathways involved in appetite signalling, glucose response, gastric processes and metabolic regulation

The gastric intestinal tract receives the food and not only digests it but also responds by signaling to the brain a feeling of satiety, telling us when to stop eating

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Excess use of alcohol or stopping alcohol abruptly can also increase the risk of seizures if you are taking Contrave