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A 2023 study on tirzepatide found that participants who switched to a placebo after losing about 21% of their body weight in three years gained back about 14% over another year

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However, tricky question here to which the answer is unknown is what are the optimal IGF-1 levels during life to live longer and healthier

A previous Phase 2 trial in 255 patients with Parkinsons disease suggested pegsebrenatide may slow the progression of motor dysfunction, with the most pronounced effects in patients younger than 60