Yes, many patients successfully lose weight on lower doses such as 0.5 mg or 1 mg weekly
The medication is building toward a true steady state, which takes roughly four to five weeks at any given dose level
Our providers prescribe FDA-approved weight-loss medications, including Mounjaro, Wegovy, Ozempic, and semaglutide, as part of a comprehensive weight-management plan tailored to each patient
When combined with a nutrient-rich diet, regular physical activity, and consistent sleep habits, B12 injection therapy can be a powerful tool for sustaining energy, supporting cognitive function, and maintaining the neurological and metabolic health your body depends on every day
Someone cleared by one may still need extra review at the other
As Dr Sullivan commented, the benefit appears to increase over time rather than fade, and that it behaves like a drug in terms of dose response. Dr Sullivan and colleagues concluded that these results support DMR as a promising, procedure-based strategy to maintain weight loss and potentially enable shorter-duration GLP-1 therapy. In a press release, Dr Sullivan noted, Finding a treatment that allows patients to stop [GLP-1] medications without weight regain or loss of metabolic benefit is a huge unmet need. She continued, These findings indicate that this minimally invasive procedure may provide lasting weight-loss maintenance. Six-month cohort data from the REMAIN-1 trial are expected to be reported late in 2026.