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This finding supports the idea that the mutation in pad2-1 close to the glutamate conjugating residues of GSH1 might influence the affinity of the enzyme for BSO, as it was proposed for cad2-1 54,71

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Rosser EC, Oleinika K, Tonon S, Doyle R, Bosma A, Carter NA et al (2014) Regulatory B cells are induced by gut microbiota-driven interleukin-1 and interleukin-6 production

When levels decline due to age, stress, or illness, biological function suffers