The STEP trial program, conducted from 2018 to 2021, enrolled over 4,600 adults with obesity or weight-related conditions
To assess the potential anti-inflammatory activity of these newly developed analogs, levels of TNF-, PGE2, and IL-6 were evaluated
"In patients with diabetes, GLP-1 RA initiation similarly resulted in a lower risk of requiring extra glucose-lowering therapy, but there was no difference in nonadherence rates when compared to metformin initiation," the researchers wrote
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Strategies like resistance training and high-quality protein intake are essential to maintain muscle during therapy
