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Searches were conducted in PubMed, Scopus, and Web of Science through November 2025, supplemented by snowball methods, focusing on studies investigating antioxidant treatments in humans exposed to hypobaric or high-altitude hypoxia

Current recommendations for muscle preservation during weight loss range from 1.2-2.0g protein per kilogram of body weight daily, with higher intake better for preserving lean mass

We see four broad scenarios

Since the first GLP-1R agonist, exenatide, was approved for the treatment of T2DM in 2005, a variety of GLP-1R agonists such as liraglutide and dulaglutide have been approved

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Consult a medical doctor before starting any diet or exercise program or if you have any known or suspected medical condition(s), and/or if you are taking any prescription or medication(s)