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Chawla SP, Cranmer LD, Van Tine BA, Reed DR, Okuno SH, Butrynski JE, et al

2011 Jan

278 : 4016240168 Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G and Berg L (1991) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

Clinical data demonstrates that most gastrointestinal symptoms are short-lived: Nausea: Median duration of 8 days per episode, with most occurrences during the first 4-8 weeks of therapy or immediately following dose increases

It acts on kisspeptin receptors in the hypothalamus to increase GnRH secretion, which in turn shapes the timing and amplitude of LH/FSH release

Festa RA, Thiele DJ