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Carrier systems for advanced drug delivery: improving drug solubility/bioavailability and administration routes

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The importance of SOCS2-mediated degradation of GHR has recently been underscored by a study showing that this was the key mechanism that causes an increased risk of developing lung cancer in individuals that carry an SNP in GHR resulting the in the amino acid change P495T in the GHR ICD

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Ipamorelin is another synthetic peptide that may interact with pituitary cells, although it appears to do so by triggering a different receptor called the growth hormone secretagogue (GHS) receptor