After matching, the study included 162,253 case and control patients
Segn las guas actuales de la American Diabetes Association (ADA), estos medicamentos pueden considerarse como terapia inicial o adicional en pacientes con diabetes tipo 2, especialmente aquellos con enfermedad cardiovascular establecida, alto riesgo cardiovascular, enfermedad renal crnica o insuficiencia cardaca, independientemente del uso de metformina
Like RAASis, after an initial reversible hemodynamic dip in GFR, further loss of GFR was substantially reduced in the SGLT2i group [54]
Those taking SGLT2 inhibitors alongside GLP-1/GIP medications face additional risks, including increased urination and potential for euglycemic diabetic ketoacidosis if severely dehydrated
Acylation of the incretin peptide exendin-4 directly impacts glucagon-like peptide-1 receptor signaling and trafficking
Carraro-Lacroix, L