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Evidence suggests GLP-1 medications can reduce inflammation, pain, and disease activity in several forms of arthritis, especially when obesity or insulin resistance is also present

The Wegovy pill, which is made by Novo Nordisk, is an FDA-approved oral semaglutide medication for adults with overweight or obesity

That does not mean retatrutide should be framed as unsafe

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In the systemic circulation, endothelial dysfunction, detectable in healthy individuals with normal brachial blood pressure, is associated with increased central pulse pressure and systemic arterial stiffening