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Glutathione may be responsible for several vital roles within a cell besides antioxidation: 17 Maintenance of the redox state (chemical reactions in which the oxidation state of atoms are modified) Modulation of the immune response Detoxification of foreign bacteria and viruses Research has demonstrated that glutathione deficiency may be a factor in many chronic conditions

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Senolytic FOXO4-DRI can inhibit FOXO4 binding by disrupting the p53-FOXO4 interaction and selectively cause apoptosis via p53 nuclear exclusion in senescent cells and aging mouse models, which may be a promising approach for preventing senescence 11