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These variations significantly influence the role of GLP-1 in regulating islet function and glucose homeostasis

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This low concentration of acetate is attributed to the intermolecular neutralization of the N-terminal amino group and the -amino group of lysine by carboxylate groups on the C-terminal or on the side chain of the aspartate and glutamate residues

In summation, alterations in redox balance by exposure to ROS cause dose dependent changes in GSH:GSSG ratios, which can potentially influence a number of target proteins by causing oxidation and disulfide exchange reactions at specific cysteine residues