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Q4 2026 (earliest): NDA filing with the FDA for the weight-management indication

Ally Hirschlag Tester Ally Hirschlag is an award-winning journalist with over 10 years of experience editing and writing health, fitness, beauty, lifestyle, and science content

Gabel says, Our metabolism slows down as we age

The practical goal is to reduce avoidable contributors: titrate thoughtfully rather than racing to the highest dose, avoid unnecessarily rapid weight loss, prioritize adequate protein, perform resistance training to preserve lean tissue, and monitor for iron, zinc, vitamin D, vitamin B12, vitamin A, and other deficiencies when intake is substantially reduced

doi:10.2337/diabetes.52.5.1176 142

Supervised weight management in Singapore particularly benefits PCOS patients, as excess weight worsens insulin resistance and hormonal imbalance