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Retatrutide is a triple receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, whereas semaglutide activates only the GLP-1 receptor and tirzepatide activates GLP-1 and GIP receptors

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Toresson und andere: Glucagon-like peptide-1 receptor agonists and risk of major adverse liver outcomes in patients with chronic liver disease and type 2 diabetes

22,23 In the liver, GLP-1RAs can also decrease hepatic gluconeogenesis and enhance glucose uptake, which can improve circulating glucose levels

Because GLP-1s encourage lower food intake, what you do put into your body must be nutrient-dense, supportive of your overall health and capable of overcoming common GLP-1 side effects

In others, it may not provide the benefits you are hoping for