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The resulting cellular loss compromises BBB integrity and is associated with elevated NO release (Kumar Nelson et al., 2024)

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CLINUVELs lead therapy, SCENESSE (afamelanotide 16mg), is approved for commercial distribution in Europe, the USA, Israel and Australia as the worlds first systemic photoprotective drug for the prevention of phototoxicity (anaphylactoid reactions and burns) in adult patients with erythropoietic protoporphyria (EPP)

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