Evidence tier: small randomized trial, Russian, unreplicated in the West
& Kelly, M
Vitamin B6, in the form of pyridoxal-5'-phosphate, is the cofactor for 5 enzymes in the -glutamyl cycle and trans-sulphuration pathway: cystathionine -synthase, cystathione -lyase, cytoplasmic and mitochondrial serine hydroxymethyltransferase and glycine decarboxylase in the mitochondria
Monitor renal function in patients reporting adverse reactions to Wegovy that could lead to volume depletion, especially during initiation and escalation of Wegovy Severe Gastrointestinal Adverse Reactions: Use of Wegovy has been associated with gastrointestinal adverse reactions, sometimes severe
MRCP (UK), FRCP, Lukas Radbruch, Prof
44/46 patients treated with OS achieved a mW of 89.2 14.0 kg and mBMI of 31.5 4.3 kg/m 2 with a mWL of 10.7 6.5 kg ( 10.4 5.8%)