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The presence of IGF-1 and IGFBP in the IPM, together with the presence of IGF-1 receptors on both photoreceptor and RPE cells [36], suggests the presence of an outer retina autocrine-paracrine system

Tirzepatide offers several practical benefits that may support long-term treatment adherence: Once-weekly dosing , which may be easier to maintain than medications that require daily use

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J Clin Endocrinol Metab 80: 952-957, 1995

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However, post-market surveillance has identified rare cases, prompting the FDA to strengthen product labeling