Chemically it is a spiro-compound built around an indane and piperidine framework (its formal name references a spiro-1H-indene-piperidine core), formulated as a mesylate salt for oral use
Kornblau SM, Vu HT, Ruvolo P, Estrov Z, O'Brien S, Cortes J, Kantarjian H, Andreeff M , May WS
Fewer openings mean more stable temperatures
Despite the benefits of storing RBCs in these novel formulations, conventional solutions are still in use (SAGM in Europe and Canada and CPDA-1 in the United States)
Different types have been reported according to their differentiation: fibroblastic/myofibroblastic, neural, smooth muscle, ganglionic, rhabdomyoblastic, and neocartilage or chondroid differentiation
[DOI] [PMC free article] [PubMed] [Google Scholar] Tobiume K, Saitoh M and Ichijo H