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Patient adherence Ultimately, patient adherence may be influenced by the physical properties of the formulation

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Valproic acid is contraindicated in patients with known hypersensitivity to the drug [seeWarnings and Precautions (5.12)]

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This mechanistic synergy, first characterised in foundational studies of GHRH and GHRP co-administration, provides the physiological and pharmacological rationale for the combination as a research tool for studying maximal physiological GH pulse generation and GH axis pharmacology