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Patients with high-responder variants may achieve greater kidney-protective benefits at lower doses, reducing unnecessary medication exposure

Keeping blood sugar in check can prevent complications like nerve damage, kidney problems, and heart disease

For instance, it has been shown that after an experimental psychologic stress, the evoked cortisol response in fatigued breast cancer survivors is much smaller than that in nonfatigued ones, pointing to the involvement of the HPA axis in cancer-related fatigue (286)

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Semaglutide treatment resulted in a 24% reduction in major kidney disease, a composite of kidney failure, at least a 50% reduction in estimated glomerular filtration rate from baseline or death from kidney-related or cardiovascular causes