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Analytical evaluation typically includes confirmation of compound identity, purity assessment using high-performance liquid chromatography (HPLC), and molecular mass verification via mass spectrometry

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Specifically, L2-Cmu was engineered as a human/murine chimera (i.e., reverse chimeric antibody), such that the complementary-determining regions (CDRs) were engineered into a new framework in which the entirety of the variable regions are human and the constant regions are mouse