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Dillmann, W

The polymer backbone covalently integrates an L-buthionine sulfoximine prodrug to inhibit glutathione biosynthesis, and the nanoparticle matrix encapsulates an elesclomol-copper complex to promote intratumoral copper accumulation

[2] The anti-inflammatory dimension dampening of pro-inflammatory cytokine signaling and support of antioxidant defenses is proposed as the mechanism that keeps the repair environment from tipping into chronic inflammation and fibrosis

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Mice were monitored for health issues daily, and cages were replaced biweekly