surpass cvot tirzepatide results Systolic blood pressure reduction with in patients with type 2 diabetes: insights from clinical program | Cardiovascular Diabetology Original Article: Cardiovascular Outcomes with

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Neuropharmacology 80 , 115132 (2014)

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The limited absorption of the nasal cavity restricts the amount of drug being effectively absorbed, making class I drugs (high permeability, high solubility), according to the Biopharmaceutics Drug Disposition Classification System (BDDCS), particularly suitable for nasal delivery (Ugwoke et al., 2001)

doi: 10.1161/01.cir.103.22.2717 216 ZhangHSCaoEHQinJF

This glucose-dependent action helps reduce hypoglycaemia risk