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Postmarketing surveillance and observational studies have reported cases of pancreatitis in patients receiving GLP-1 receptor agonists, although a causal relationship remains debated and confounded by underlying disease risk factors (Drucker, 2018)
A Phase 2 trial published in The New England Journal of Medicine (Jastreboff et al., 2023) reported a mean body weight reduction of approximately 24% at the highest dose over 48 weeks in participants without type 2 diabetes results that attracted considerable scientific interest
A retrospective cohort study, by Dotan et al., involving 318 patients, further revealed that treatment with GLP-1 RAs was associated with a reduced risk of major adverse cardiovascular events (MACEs) and all-cause mortality among solid organ transplant recipients, including kidney, lung, liver, and heart transplants [23]
Tirzepatide: Which Is Better
I also suspect that I spent more time in the ravenously hungry zone because I felt hungry often but would ignore it (because I didnt feel like doing anything)
