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A clinical trial in Parkinsons disease patients using systemic administrations of the GLP1-R agonist exendin-4 in an extended release formulation has demonstrated clinical efficacy (Athauda et al, 2017)

The most commonly prescribed options include Semaglutide (marketed as Wegovy or Ozempic) and Liraglutide (marketed as Saxenda), which differ in dosing frequency and strength

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So when glucose levels rise, the body needs more insulin, and GLP-1 or Ozempic (its mimicker) helps the pancreas release insulin, Korner explains

Jelly legs refers to the sensation of weak, wobbly, or unstable legs, often described as feeling like they are going to collapse