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GLP-1 therapy works in significant part by weakening the body's normal appetite feedback, the homeostatic system that increases hunger as weight is lost

doi: 10.3389/fimmu.2013.00470 54 De CandiaP.PrattichizzoF.GaravelliS.MatareseG

Studies were divided in cognitive disorders, substance-use disorders, psychotic disorders, mood and anxiety disorders, and eating disorders

Medical societies have expressed concern about the use of these medications for purely cosmetic weight loss in people who are not overweight or only mildly overweight

Nevertheless, peptide-based obesity treatments are pushing forward

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