In contrast, the strategy behind active surveillance/active monitoring is to defer therapy for clinically localized disease but regularly follow the patient and initiate local therapy with curative intent if there are any signs of local tumor progression.[6-9] The intention is to avoid the morbidity of therapy in men who have indolent or nonprogressive disease but preserve the ability to cure them should the tumor progress
In the context where immune checkpoint blockade (ICB) has demonstrated remarkable efficacy in cancer immunotherapy, several studies have revealed the reduced effectiveness of anti-PD-1/PD-L1 therapy in aged mice and elderly patients, 207,208,209 leading to treatment resistance
What Is Prior Authorization and Why Does It Matter
Seek immediate medical attention for signs of severe dehydration, diabetic ketoacidosis, or severe flank pain with fever
Semaglutide Tirzepatide and semaglutide work through related but distinct pathways
How Ipamorelin Works in the Body Ipamorelin mimics the action of ghrelin , a hormone known for stimulating both appetite and growth hormone release