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Screening After deduplication, in which we used Endnote online 20 (Clarivate, Philadelphia, PA) [6], two independent researchers (SO and JM) screened the studies by title and abstract, and disagreements were solved by a third (JC)

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When to seek medical attention: Persistent vomiting preventing adequate fluid intake Severe abdominal pain, particularly if localized to the upper right quadrant (potential gallbladder issues) Severe pain in the upper abdomen radiating to the back (possible pancreatitis) Signs of dehydration (dark urine, dizziness, decreased urination) Inability to tolerate any food or liquids for more than 24 hours Severe constipation with abdominal distension or vomiting (possible ileus/obstruction) Yellowing of skin/eyes with fever and abdominal pain Patients with significant vomiting or diarrhea should be monitored for signs of acute kidney injury, particularly those with pre-existing renal impairment or taking medications that affect kidney function