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PI3K inhibitors, such as 3-methyladenine (3-MA), wortmannin, and LY294002, target autophagy by inhibiting Vps34, a component of class III PI3K, thereby blocking the formation of autophagosomes [96]

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In other embodiments, an additional surfactant (co-surfactant) and/or buffering agent is combined with one or more of the pharmaceutically acceptable vehicles previously described herein so that the surfactant and/or buffering agent maintains the product at an optimal pH for stability