Beyond weight management, Semaglutide has demonstrated cardiovascular risk reduction in patients with type 2 diabetes, making it an attractive option for individuals with obesity-related comorbidities
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Cagliflozin (Cana) was effective in improving glucose metabolism disorders in patients with T2DM, which may be attributed to the restoration of the balance between the gut and oral microbial communities
In such patients, the ADA-EASD 2022 consensus report also recommends the combination of GLP-1RAs and SGLT2is when hemoglobin A1c (HbA1c) target is not reached with a drug from one of the two classes [6]
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