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doi: 10.1126/science.aad8711 297 HuangYYanJLiQLiJGongSZhouHet al

You may have a deficiency if you are vegan, dont eat enough B12 rich food, or if you have other health conditions which mean you are unable to absorb it properly

pharmacogenomics J (2012) 12(5):38694

Ofoe R, Thomas RH, Asiedu SK, Wang-Pruski G, Fofana B, Lord A (2023) Aluminum in plant: benefits, toxicity and tolerance mechanisms

Where it has been useful is in individuals who have weight to lose and perhaps struggle with higher blood sugar and poor food compliance, which makes sticking to a low histamine diet (or any more restrictive diet) more challenging

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