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However: Long-term safety data are limited

Get emergency help if someone is hard to wake, breathing slowly, vomiting often, pale or blue, confused, or having seizures after drinking

PMID 16517654

however, variations in concentration ranges, exposure times, delivery methods, and oxidative stress inducers influence effect sizes and statistical power

Moreover, intra-articular injection of monoiodoacetate (MIA) induces loss of articular cartilage with subchondral bone lesions that mimic those of human OA and This model offers a rapid and minimally invasive method to reproduce OA-like lesions in a rodent species [13]