Journal of Parkinsons Disease
doi: 10.3389/fphar.2024.1439536 Received 13 June 2024 Accepted 19 September 2024 Published 08 October 2024 Volume 15 - 2024 Edited by Karim Hosni, Institut National de Recherche et d'Analyse Physico-Chimique (INRAP), Tunisia Reviewed by Lourdes Franco, Faculty of Medicine.University of Extremadura, Spain Jolanta Orze-Gryglewska, University of Gdansk, Poland Updates Copyright 2024 Mu, Qu, Yin, Wang, Liu and Liu
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lceras crnicas (venosas, presin, diabticas)
Clinical trials have used doses of 25-30 nmol/kg by IV infusion (Schneider-Helmert et al., 1981Subcutaneous administration and oral intestinal absorption have also been studied
These inhibitors directly act on HDACs and can also indirectly affect the activity of HATs, which modulate the level of acetylation and deacetylation in the cell nucleus
