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An in vitro study found that prolonged oven heating or boiling (i.e., six minutes or longer) suppressed the inhibitory effect of uncrushed and crushed garlic on platelet aggregation, but crushed garlic retained more anti-aggregatory activity compared to uncrushed garlic (136)

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Moreover, dose-response analysis demonstrated that L-carnitine supplementation at doses of equal 2 g/day has an optimal effect on insulin levels

[ 12 , 16 ] Researchers hypothesize that this mechanism could contribute to some of the sleep-related effects reported in early studies