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Intracellular delivery of therapeutic antibodies into specific cells using antibody-peptide fusions

Mechanistically, the expression of GLS1 is regulated indirectly by Myc (via repression of miR-23a and miR-23b) and mTORC1 11,12

[1] Cell Line:Senescent Leydig cells Concentration:25 mM Incubation Time:3 days Result:Reduced the viability of senescent as compared to normal TM3 Leydig cells

Foster, G

*Endocrine Practice*, 24(7), 633-650

Myosteatosis alters muscle fiber composition and organization, with a decrease in oxidative, insulin-sensitive fibers and a concomitant increase in relatively fast-fatiguing glycolytic fibers, paralleling the effects observed in obesity and aging