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Studies indicate that many of the positive benefits observed with Berberine may be related to its interaction AMPK (adenosine monophosphate-activated protein kinase) an important enzyme that is expressed in a number of tissues, including theliver,brain, andskeletal muscle

PMID: 32347396

They can even help you switch to an alternative medication if appropriate

Anyone with a BMI of 30 or above, or 27 with at least one weight-related comorbidity, meets the standard prescribing criteria for GLP-1 therapy