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Compare this to 1820 percent over 72 weeks for tirzepatide, or 14.9 percent over 68 weeks with semaglutide (both in phase III trials)

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Am J Physiol Endocrinol Metabol

The two principal incretins , GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), act together with insulin and glucagon to regulate glucose homeostasis and energy balance [1]

Participants who skipped titration steps experienced nearly double the GI symptom rates

Effect of linagliptin vs glimepiride on major adverse cardiovascular outcomes in patients with type 2 diabetes: the CAROLINA randomized clinical trial